Thanks for the comments (in both Chassis & Foamie blogs), all very useful.
I was expecting a lot of "nay-say" on the aluminum due to corrosion at joints with steel parts. Here is a page from a trailer manufacturer ?(Great Dane Trailers) with tips to minimize the problem.
http://trailer-bodybuilders.com/fabrication/how-deal-dissimilar-metalsWikipedia has a good page on Galvanic corrosion too
https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=5&cad=rja&uact=8&ved=0ahUKEwi52N3nvdzMAhWEPz4KHfuvBb8QFgg5MAQ&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FGalvanic_corrosion&usg=AFQjCNG2PU0Jpb-1kHTX5AplrylhkZGQvwLooks like a challenge but then again, all-steel trailers have rust issues. I have some vinyl flashing I hope is ok for surface isolation. It would be nice to get some nylon shoulder washers for the hole through the Al to isolate it from the bolt threads. I am not familiar with PTFE paste, is it some Teflon product?
I had heard about aluminum problems with regard to fatigue and cracks (hard to forget what happened to the first commercial jet airliner, the British Comet)! I just didn't think it was a problem with trailers until Shadow Catcher's comments (Foamie Blog). I'm hopeful it will not be a problem if I stay light.
Still undecided which way to choose, it’s hard to give up on saving a hundred pounds! I am not sure if a bolt-together aluminum trailer is a wise thing or not. While most (if not all) aluminum trailers deal with different metal for the axle & suspension, the ones I've seen are welded witch avoids a lot of joints I will have to deal with in these designs.